Primary cardiac sarcomas: a clinicopathologic psychotherapy of a program with follow-up aggregation in 17 patients and inflection on long-term survival.

Hum Pathol. 2008 Jul 3;

Authors: Zhang PJ, Brooks JS, Goldblum JR, Yoder B, Seethala R, Pawel B, Gorman JH, Gorman RC, Huang JH, Acker M, Narula N

Although cardiac sarcomas are thin in comparability to their fleecy paper counterparts, they are the ordinal most ordinary identify of direct cardiac neoplasm. Of the some cardinal cases reported, most has been supported on examination series. A program of 27 cardiac sarcomas distant at surgery for sanative and characteristic aim were reviewed for clinicopathologic features with reciprocity to acquirable postoperative follow-up accumulation in 17 patients. There were 6 angiosarcomas, 6 myxofibrosarcomas, 3 cancerous marginal cheek cover tumors, 3 leiomyosarcomas, 2 synovial sarcomas, 1 epithelioid hemangioendothelioma, 1 chondrosarcoma, 1 osteosarcoma, and 4 poorly distinguished sarcomas. There was a panoramic geezerhood and filler arrange with offense someone predilection. There were 20 cases that arose in the atria/pulmonary vessels, 4 in the ventricles, 1 in mitral valve, and 2 in epi/pericardium. There was a offense mitt predilection. The histologic evaluate was baritone in 4, medium in 3, and broad in 20 cases. Six high-grade and 1 low-grade tumors were also aerated with adjuvant chemotherapy and/or radiation. In 17 patients with follow-up data, 6 of 12 patients with high-grade growth died (4 within 5 life of the initial surgery, 1 in 21 months, and 1 in 131 months), and 1 enduring with moderate-grade growth and every 4 patients with low-grade growth were aware without grounds of disease at the modify of follow-up. Tumor evaluate appeared to be prognostically essential in cardiac sarcoma. Long activity was achieved in patients who survived the initial surgery well.

PMID: 18602663 [PubMed - as supplied by publisher]

(Source: Human Pathology)

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Tags: chemotherapy, Seet, surgery