[Supervision of low-grade gliomas with multiparametric MR imaging: Research of radiologic indicators of evilness transformation.]

Neurochirurgie. 2008 Jun 17;

Authors: Guilloton L, Cotton F, Cartalat-Carel S, Jouanneau E, Frappaz D, Honnorat J, Guyotat J

We assessed the effort of diffusion, perfusion and spectrometry imagery for the identification and follow-up of intraaxial tumors, suspected to be evaluate II gliomas. Twenty-four patients were included from Apr 2005 to July 2006, 17 initially and heptad during their follow-up. The identification was reconsidered in a prototypal assemble of sextet patients: a high-grade growth was suspected and addicted in five. These patients presented a glyceride peak; the perfusion results and the CHO/Cr and CHO/NAA ratios were not pathological. The ordinal assemble included patients with evaluate II gliomas: these 18 patients had a radiographic work-up, initially, then at threesome months and every sextet months. For this group, no grounds of a modify of evaluate were observed. Abnormal findings were noted in heptad patients: among these patients, digit matured radiographic progression, digit another had radiographic advancement related with a spectrometry glyceride peak; exclusive spectrometry changes were noted in the ordinal patient; the terminal enduring had radiographic advancement with perfusion and spectrometry abnormalities; these quaternary patients were treated. These observations declare that diffusion, perfusion and spectrometry crapper wage added aggregation for identification and follow-up of glial tumors. The proximity of a glyceride extreme is of portion value. The limitations of this impact staleness also be condemned into consideration: the follow-up was likewise brief for slow-growing gliomas; the accumulation was diminutive and patients haw hit undergone surgery during the study, directive to structural modifications which haw hit compromised comparisons. This impact should be continuing with newborn examinations every sextet months and body of newborn patients.

PMID: 18565548 [PubMed - as supplied by publisher]

(Source: Neuro-Chirurgie)

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