Prevalence of abnormal glucose metabolism in atrial fibrillation: a case control study in 75-year old subjects
admin Background:
The figure of atrial arrhythmia (AF) is crescendo concern panoramic and amongst factors that exasperate the venture is diabetes mellitus (DM), also in pestilential development.
However, though DM is a potentially modifiable venture bourgeois for AF, few, if any, studies hit explored the figure of undiagnosed dysglycaemia among subjects with AF or if continuance of AF are attendant to parameters of glycaemia or dysglycaemia prevalence.
Methods:
In this housing curb study, amongst 75-year older subjects with and without AF, the figure of dysglycaemia, i.e., broken abstinence glycaemia, broken glucose temperament or DM, according to World Health Organisation criteria was assessed by a 75-g effort glucose temperament effort (OGTT).
Results:
Prevalence of undiagnosed DM among the 108 subjects (male/female 73/35, BMI 25.4+/-3.2) without and the 46 (male/female 34/12, BMI 25.3+/-3.7) with AF (median AF continuance fivesome years) where 3.7% and 13.0%, respectively (p=0.031, Odds ratio (OR) 3.86 (95% Confidence quantity [CI]: 1.01, 16.25)) whereas the coverall figure of dysglycaemia (prediabetes and DM) where kindred (respectively 43.5% and 39.1%, p=0.46, OR 0.83 [95% CI: 0.41, 1.69]). Patients with AF continuance >= 5 eld had still a higher dysglycaemia figure (61.1% [DM 22.2%, prediabetes 38.9%]) as compared to AF continuance < 5 eld (25% [DM 7.1%, prediabetes 17.9%], p=0.0014, OR 4.7 [95% CI: 1.30, 16.90]) or no AF (p=0.17, OR 2.04 [95% CI: 0.73, 5.66]). There was also a momentous reciprocity between the continuance of AF and HbA1c (r=0.408, p=0.005) and abstinence glucose levels (r=0.353, p=0.016).
Conclusions:
AF is related with habitual symptom amongst 75-year older subjects. Prediabetes and DM should be pro-actively assessed if AF continuance >= 5 years.
Posted in Cardiology |