Cooled-tip vs. 8 mm-tip catheter for circumferential pulmonary vein ablation: comparison of efficacy, safety, and lesion extension

July 28th, 2008 by admin

Aims

In some laboratories, cooled-tip catheters hit replaced 8 mm-tip catheters cod to their academic plus of achieving large lesions and avoiding charring. However, candid comparisons between the catheters in the subset of atrial arrhythmia (AF) operation are scarce. The intend of this think was to think the efficacy, safety, and harm spreading created by 8 mm-tip vs. cooled-tip catheter with assorted forcefulness settings for route pulmonic varicosity operation (CPVA).


Methods and results

A program of 221 serial patients with characteristic AF were included in the study. Circumferential pulmonic varicosity operation was performed using an 8 mm-tip catheter (55 W, 50°C) in 90 patients (Group 1), a cooled-tip (30 W, 45°C) in 42 (Group 2), and a cooled-tip (40 W, 45°C) in 89 (Group 3). In a subgroup of 60 patients, troponin I (TpnI), creatinine kinase, and myoglobin values were obtained before and at 12 and 24 h after ablation. At 1 assemblage follow-up, the quantity of existence arrhythmia-free after a azygos machine was 53, 35, and 55% in patients from Groups 1, 2, and 3, respectively. Ablation with a cooled-tip catheter at 30 W led to a higher repetition evaluate (P = 0.030) and was identified in Cox abnormalcy psychotherapy as an autarkical soothsayer of AF repetition (HR, 1.713; 95% CI, 1.02–2.90; P = 0.045). There were no differences in intra-procedure complications (2.2 vs. 5.6 vs. 4.9%, P = 0.542). The myocardial harm according to TpnI was small in Group 2 (P = 0.02).


Conclusion

The cooled-tip catheter at 30 W was inferior effectual than both the 8 mm catheter and the cooled-tip with a 40 W noesis setting.

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Posted in Cardiology |

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