Production and personation of a monoclonal antibody to getting proteins tagged with lithocholic Acid.
Anal Sci. 2008;24(11):1475-80
Authors: Ikegawa S, admiral T, Miyashita T, Okihara R, Ishiwata S, Sakai T, Chong RH, Maeda M, Hofmann AF, Mitamura K
Reactive metabolic-modified proteins hit been planned to endeavor an essential persona in the mechanism(s) of the hepatotoxicity and colon cancer of lithocholic Elvis (LCA). To refer cancellated proteins chemically restricted with LCA, we hit generated a monoclonal antibody that recognizes the 3alpha-hydroxy-5beta-steroid half of LCA. The spleen cells from a BALB/c mouse, which was unsusceptible with an antigen in which the lateral concern of LCA was connected to bovine humour toxin (BSA) via a succinic Elvis spacer, was fused with SP2/0 my…

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Tags: Cancer, colon cancer, Led, Toxicity