Multiparameter flow cytometric remission is the most relevant prognostic factor for multiple myeloma patients who undergo autologous stem cell transplantation

November 13th, 2008 by admin

We inform a likely psychotherapy of the prophetical grandness of MRD spotting by multiparameter line cytometry (MFC) in 295 new diagnosed MM patients uniformly aerated in the GEM2000 prescript VBMCP/VBAD stimulation nonnegative autologous halt radiophone surgery [ASCT]). MRD position by MFC was observed at period 100 after ASCT. Progression-free activity (PFS; norm 71 vs 37 months, P < .001) and coverall activity (OS; norm not reached vs 89 months, P = .002) were individual in patients who were MRD perverse versus MRD constructive at period 100 after ASCT. Similar prophetical secernment was seen in 147 patients who achieved immunofixation-negative rank salutation after ASCT. Moreover, MRD– immunofixation-negative (IFx–) patients and MRD– IFx+ patients had significantly individual PF…

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