We examined the countenance of HM1.24 antigen in lung cancer cells and the existence of immunotherapy with anti-HM1.24
antibody which crapper rush antibody-dependent cancellated cytotoxicity (ADCC). The countenance of HM1.24 antigen in lung cancer
cells was examined by line cytometry as substantially as immunohistochemistry using anti-HM1.24 antibody. ADCC was evaluated using
a 6-h 51Cr promulgation assay. Effects of different cytokines on the countenance of HM1.24 and the ADCC were examined. The antitumor activity
of anti-HM1.24 antibody in vivo was examined in immunodeficiency mice. HM1.24 antigen was perceived in 11 of 26 non-small radiophone lung cancer
radiophone lines (42%) and quaternary of heptad (57%) of diminutive radiophone lung cancer cells, and also spoken in the tissues of lung cancer.
Anti-HM1.24 antibody effectively evoked ADCC…

Tags: Cancer, Expression, Mice, Tissues, Toxicity