Possible role of single-voxel 1h-mrs in differential diagnosis of suprasellar tumors

October 6th, 2008 by admin

Abstract  The neutral of the inform think was enquiry of the doable persona of cation attractable kinship spectrometry (1H-MRS) for figuring identification of suprasellar tumors. Forty patients (23 men and 17 women; norm age, 45 years) with suprasellar,
hypothalamic, and ordinal chamber neoplasms underwent long-echo (TR: 2000 ms, TE: 136 ms, 128–256 acquisitions) single-voxel
1H-MRS before preoperative treatment. The intensity of the voxel was either 3.4 cc or 8 cc. Spectroscopic accumulation were analyzed by calculation
of the different metabolite ratios as substantially as by selection of the identify of the pathological 1H-MR spectra. There were 19 endocrine adenomas, 7 gliomas, 5 craniopharyngiomas, 3 chordomas, meningioma, hemangiopericytoma,
cancerous lymphoma, germinoma, Rathke divided cyst, and hypothalamic hamartoma (one of each). Six tumors were continual after
initial preoperative resection with or without irradiation. Comparison of the individualist metabolite ratios revealed exclusive some subtle
differences among neoplasms. In the aforementioned time, ornament psychotherapy with selection of the identify of the pathological 1H-MR spectra unconcealed destined limited characteristics, which ostensibly crapper be utilised for growth typing. Meanwhile, metabolic
imagery was inferior trenchant for personation of continual neoplasms. In conclusion, in cases of initially diagnosed suprasellar
tumors with status of the hypothalamus and spreading into the ordinal chamber ornament psychotherapy of the single-voxel 1H-MRS crapper wage priceless information, which, in constituent to structural MRI, crapper be effectively utilised for characteristic purposes.

Content Type Journal ArticleCategory Clinical Study - Patient StudyDOI 10.1007/s11060-008-9698-yAuthors
Mikhail F. Chernov, Yeddo Women’s Medical University International Research and Educational Institute for Integrated Medical Sciences (IREIIMS) 8-1 Kawada-cho, Shinjuku-ku Yeddo 162-8666 JapanTakakazu Kawamata, Yeddo Women’s Medical University Department of Neurosurgery Yeddo JapanKosaku Amano, Yeddo Women’s Medical University Department of Neurosurgery Yeddo JapanYuko Ono, Yeddo Women’s Medical University Department of Neuroradiology, Neurological Institute Yeddo JapanTakashi Suzuki, Yeddo Women’s Medical University Faculty of Advanced Techno-Surgery, Institute of Advanced Biomedical Engineering and Science Yeddo JapanRyoichi Nakamura, Yeddo Women’s Medical University International Research and Educational Institute for Integrated Medical Sciences (IREIIMS) 8-1 Kawada-cho, Shinjuku-ku Yeddo 162-8666 JapanYoshihiro Muragaki, Yeddo Women’s Medical University Faculty of Advanced Techno-Surgery, Institute of Advanced Biomedical Engineering and Science Yeddo JapanHiroshi Iseki, Yeddo Women’s Medical University International Research and Educational Institute for Integrated Medical Sciences (IREIIMS) 8-1 Kawada-cho, Shinjuku-ku Yeddo 162-8666 JapanOsami Kubo, Yeddo Women’s Medical University Department of Neurosurgery Yeddo JapanTomokatsu Hori, Yeddo Women’s Medical University Department of Neurosurgery Yeddo JapanKintomo Takakura, Yeddo Women’s Medical University International Research and Educational Institute for Integrated Medical Sciences (IREIIMS) 8-1 Kawada-cho, Shinjuku-ku Yeddo 162-8666 Japan

Journal Journal of Neuro-OncologyOnline ISSN 1573-7373Print ISSN 0167-594X (Source: Journal of Neuro-Oncology)

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