Elevated granulocyte colony-stimulating factor, non-infectious leukocytosis and fevers in a patient with multiple myeloma

September 25th, 2008 by admin

Abstract  Background: We inform the housing of a 56-year-old phallic with binary myeloma in whom continual fevers and leukocytosis delayed
potentially trenchant chemotherapy cod to anxiety for astir infection. Design and measurements: A complete communicable workup,
including CT and tomography scans, was negative. The enduring was yet institute to hit an elevated humour granulocyte colony-stimulating
bourgeois (G-CSF) of 113 pg/ml (normal arrange 0.0 – 39.1 pg/ml), which was probable the drive of his continual leukocytosis and
fevers. Multiagent chemotherapy was initiated, and the fevers resolute in the incoming 4 days. Results: Leukocyte concentrations
trended downbound after institution of chemotherapy, but it is doubtful how such of the fall was imputable to immunosuppression.
Conclusion: We inform this well-documented housing to shew that G-CSF creation should be thoughtful as a drive of unexplained
feverishness and leukocytosis in patients with binary myeloma to preclude incongruous and suspended expressed identification and treatment.

Content Type Journal ArticleCategory Case Reports/Clinical VignettesDOI 10.1007/s11606-008-0789-4Authors
Meghan M. Sebasky, University of Minnesota Medical Center metropolis MN USAPankaj Gupta, Veterans Affairs Medical Center metropolis MN USAGregory A. Filice, Veterans Affairs Medical Center metropolis MN USA

Journal Journal of General Internal MedicineOnline ISSN 1525-1497Print ISSN 0884-8734 (Source: Journal of General Internal Medicine)

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