The additional value of ct images interpretation in the differential diagnosis of benign vs. malignant primary bone lesions with 18f-fdg-pet/ct

August 25th, 2008 by admin

Abstract
Objective  To appraise the continuance of a sacred rendering of the CT images in the figuring identification of harmless vs. malignant
direct pearl lesions with 18fluorodeoxyglucose-positron emergence tomography/computed picturing (18F-FDG-PET/CT).

Materials and methods  In 50 serial patients (21 women, 29 men, stingy geezerhood 36.9, geezerhood arrange 11–72) with suspected direct pearl neoplasm conventional
radiographs and 18F-FDG-PET/CT were performed. Differentiation of harmless and cancerous lesions was severally performed on
customary radiographs, tomography lonely (PET), and PET/CT with limited categorization of the CT part. Histology served as the standard
of meaning in 46 cases, clinical, and imagery follow-up in quaternary cases.

Results  According to the accepted of reference, customary 17 lesions were harmless and 33 malignant. Sensitivity, specificity, and
quality in categorization of evilness was 85%, 65% and 78% for customary radiographs, 85%, 35% and 68% for tomography lonely and
91%, 77% and 86% for compounded PET/CT. Median SUVmax was 3.5 for harmless lesions (range 1.6–8.0) and 5.7 (range 0.8–41.7) for cancerous lesions.

In octad patients with pearl lesions with broad FDG-uptake (SUVmax ≥ 2.5) sacred CT rendering led to the precise identification of a harmless harm (three tough dysplasias, digit osteomyelitis,
digit aneurysmatic pearl cyst, digit tough cortical defect, 1 phosphaturic mesenchymal tumor). In quaternary patients with lesions
with baritone FDG-uptake (SUVmax < 2.5) sacred CT rendering led to the precise identification of a cancerous harm (three chondrosarcomas and digit leiomyosarcoma).
Combined PET/CT was significantly more faithful in the secernment of harmless and cancerous lesions than tomography lonely (p = .039).
There was no momentous disagreement between PET/CT and customary radiographs (p = .625).

Conclusion  Dedicated rendering of the CT conception significantly reinforced the action of FDG-PET/CT in secernment of benign
and cancerous direct pearl lesions compared to tomography alone. PET/CT more commonly distinguished harmless from cancerous primary
pearl lesions compared with customary radiographs, but this disagreement was not significant.

Content Type Journal ArticleCategory Original ArticleDOI 10.1007/s00259-008-0876-0Authors
K. Strobel, University Hospital metropolis Division of Nuclear Medicine, Department of Medical Radiology Raemistr. 100 8091 metropolis SwitzerlandU. E. Exner, University Hospital Balgrist Department of Orthopedic Surgery metropolis SwitzerlandK. D. M. Stumpe, University Hospital metropolis Division of Nuclear Medicine, Department of Medical Radiology Raemistr. 100 8091 metropolis SwitzerlandT. F. Hany, University Hospital metropolis Division of Nuclear Medicine, Department of Medical Radiology Raemistr. 100 8091 metropolis SwitzerlandB. Bode, University Hospital metropolis Institute of Surgical Pathology metropolis SwitzerlandK. Mende, University Hospital metropolis Division of Nuclear Medicine, Department of Medical Radiology Raemistr. 100 8091 metropolis SwitzerlandP. Veit-Haibach, University Hospital metropolis Division of Nuclear Medicine, Department of Medical Radiology Raemistr. 100 8091 metropolis SwitzerlandG. K. von Schulthess, University Hospital metropolis Division of Nuclear Medicine, Department of Medical Radiology Raemistr. 100 8091 metropolis SwitzerlandJuerg Hodler, University Hospital Balgrist Department of Radiology metropolis Switzerland

Journal dweller Journal of Nuclear Medicine and Molecular ImagingOnline ISSN 1619-7089Print ISSN 1619-7070 (Source: dweller Journal of Nuclear Medicine and Molecular Imaging)

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