Risk of leukemia and multiple myeloma associated with exposure to benzene and other organic solvents: evidence from the italian multicenter case-control study

July 26th, 2008 by admin

While there is a generalized consensus most the knowledge of benzol to rush accent myeloid cancer (AML), its personalty on habitual lymphoid cancer and binary myeloma (MM) are ease low debate. We conducted a population-based case-control think to appraise the connexion between danger to nonsynthetic solvents and venture of myeloid and lymphoid cancer and MM.Five cardinal eighty-six cases of cancer (and 1,278 accumulation controls), 263 cases of MM (and 1,100 accumulation controls) were collected. Experts assessed danger at individualist take to a arrange of chemicals.We institute no connexion between danger to some dissolver and AML. There were elevated saucer estimates for the associations between medium/high benzol danger and habitual lymphatic cancer (OR = 1.8, 95% CI = 0.9-3.9) and MM (OR = 1.9, 95% CI = 0.9-3.9). Risks of habitual lymphatic cancer were somewhat elevated, albeit with panoramic certainty intervals, from medium/high danger to dissolvent and solvent as well.We did not hold the famous connexion between benzol and AML, though this is probable explained by the demanding conception of benzol in Italia nearly threesome decades preceding to think initiation. Our results hold the connexion between benzene, xylene, and solvent and habitual lymphatic cancer and between benzol and MM with individual latencies than hit been observed for AML in another studies. Am. J. Ind. Med. 2008. © 2008 Wiley-Liss, Inc. (Source: dweller Journal of Industrial Medicine)

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