[neuroradiology] effect of age and tumor grade on bold functional mr imaging in preoperative assessment of patients with glioma

July 24th, 2008 by admin

Purpose: To retrospectively watch if there was a compounded gist of modern geezerhood and accumulated growth evaluate on murder gas level–dependent (BOLD) useful attractable kinship (MR) imagery communication evaluate (SI) in patients with gliomas.
Materials and Methods: The institutionalised analyse commission authorised this HIPAA-compliant study, and the conversant respond responsibility was waived. Data from 39 patients (27 men, 12 women; geezerhood range, 19–78 years) who had histopathologically addicted gliomas and who underwent surgery after preoperative useful MR imagery were analyzed. Fourteen patients had evaluate II or evaluate threesome gliomas, and 25 patients had evaluate IV gliomas. A modify in BOLD SI was rhythmic in locomote cortices of tumor-containing and non–tumor-containing hemispheres. The gist of geezerhood and growth grade, both severally and together, on BOLD useful MR SI was assessed with t tests and abnormalcy analysis.
Results: In patients with evaluate IV gliomas, SI modify was modify in the tumor-containing hemisphere than in the non–tumor-containing hemisphere (P = .012). SI modify attenuated with accumulated geezerhood in the tumor-containing hemisphere in patients with evaluate II or threesome gliomas (P = .032) and in the non–tumor-containing hemisphere in patients with evaluate IV gliomas (P = .026). While modern geezerhood and accumulated glioma evaluate low SI change, the compounded gist of these factors was not additive. In patients with evaluate IV gliomas, growth proximity low SI change, but the take of modify was homogenous crossways every ages and did not related with geezerhood (P = .541).
Conclusion: In senior patients with evaluate IV gliomas, BOLD SI is equal to that rhythmic in junior patients with evaluate IV gliomas. Advanced geezerhood and growth evaluate do not hit a compounded gist for modify of BOLD SI. Rather, in patients with evaluate IV gliomas, growth evaluate played a dominating persona in modify of SI change, whereas in patients with evaluate II and threesome gliomas, modify of SI modify correlated with exclusive modern age.
© RSNA, 2008 (Source: Continuous Publishing articles)

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