Abstract
Purpose  The intend of the think is to retrospectively analyse the quality of 11C-acetate (ACE)-positron emergence picturing (PET) for assessment of mentality glioma, in comparability with 11C-methionine (MET) and 2-deoxy-2-18F-fluoro-d-glucose (FDG).

Procedures  Fifteen patients with mentality glioma referred to initial identification were examined with ACE, MET, and FDG-PET. Five patients had
low-grade gliomas (grade II), threesome had anaplastic astrocytomas (grade III), and heptad had glioblastomas (grade IV). tomography results
were evaluated by seeable and semiquantitative analysis. For semiquantitative analysis, the standard uptake continuance (SUV)
and growth to contralateral connatural wear concern (T/N) ratio were calculated. The sense for spotting of high-grade gliomas was premeditated using seeable analysis.

Results  Sensitivities of ACE, MET, and FDG were 90%, 100%, and 40%, respectively. ACE and MET T/N ratios were significantly higher than that of FDG. ACE and FDG SUV in high-grade gliomas were significantly higher than that
in low-grade gliomas. No momentous differences were observed using MET.

Conclusions  ACE tomography is a potentially multipurpose radiotracer for sleuthing mentality gliomas and differentiating high-grade gliomas.

Content Type Journal ArticleCategory Research ArticleDOI 10.1007/s11307-008-0152-5Authors
Y. Yamamoto, Kagawa University Department of Radiology, Faculty of Medicine 1750-1 Ikenobe, Miki-cho, Kita-gun Kagawa 761-0793 JapanY. Nishiyama, Kagawa University Department of Radiology, Faculty of Medicine 1750-1 Ikenobe, Miki-cho, Kita-gun Kagawa 761-0793 JapanN. Kimura, Kagawa University Department of Radiology, Faculty of Medicine 1750-1 Ikenobe, Miki-cho, Kita-gun Kagawa 761-0793 JapanR. Kameyama, Kagawa University Department of Radiology, Faculty of Medicine 1750-1 Ikenobe, Miki-cho, Kita-gun Kagawa 761-0793 JapanN. Kawai, Kagawa University Department of Neurological Surgery, Faculty of Medicine Kagawa JapanT. Hatakeyama, Kagawa University Department of Neurological Surgery, Faculty of Medicine Kagawa JapanM. Kaji, Kagawa University Hospital Department of Pharmacy Kagawa JapanM. Ohkawa, Kagawa University Department of Radiology, Faculty of Medicine 1750-1 Ikenobe, Miki-cho, Kita-gun Kagawa 761-0793 Japan

Journal Molecular Imaging and BiologyOnline ISSN 1860-2002Print ISSN 1536-1632 (Source: Molecular Imaging and Biology)

Tags: Brain, glioma, Hospital, imaging, Led, Medicine, surgery, tomography